Did it Work? Discussing Viable Clinical Endpoints & Objective Measures to Accurately Assess Drug Efficacy in the Inner Ear
Time: 1:10 pm
day: Workshop Day
Details:
With recent developments and positive clinical results with gene therapy for inherited deafness and great progress with cell therapies and small molecules showing promise as novel therapeutics for common hearing loss. a big question remains – how can you prove that your drug worked if you don’t have a checklist?
This workshop will:
- Uncover objective measures that clinically correlate with clinical patient reported outcomes and improve structure and function
- Examine quantitative outcomes that are measurable and clinically meaningful to develop better translational endpoints (working your way back)
- Explore the gap in current criteria for predictiveness of various objective measures such as psycho-acoustics, psycho-physics, electrophysiological measures and protectiveness to allow selection of best targets and best candidates for clinical trials
- Review previously used and acceptable endpoints that show clinical benefit in various patient populations for varying hearing disorders
