DAY ONE
8:00 am Registration & Light Breakfast
8:50 am Chair’s Opening Remarks
Turning Past Failures into Future Success: Navigating the Evolving Landscape of Hearing Disorder Treatments
9:00 am Industry Leaders Fireside Chat: Exploring the Highlights & Hurdles from the Past Year to Inform Your 2025 Strategy
Synopsis
An executive panel discussion from industry leaders of the field to set the scene on the inner ear disorders therapy space. Ask your questions live to understand the expert’s thoughts on key topics including:
- Highlighting and celebrating the big wins for inner ear therapeutics in the last year
- Considering the challenges facing inner ear research including diagnostic testing, models and translational challenges
- Benchmarking lessons learned from clinical setbacks to take forward into future programs
9:30 am Innovation in the Tinnitus Space: Emerging Therapies and Strategies for Better Patient Care
Synopsis
- Evaluating innovative preclinical models for tinnitus to better understand underlying mechanisms and predict therapeutic efficacy
- Differentiating between peripheral and central causes of tinnitus to guide targeted therapeutic strategies and clinical trial design
- Exploring emerging research on the molecular and genetic factors contributing to inner ear dysfunction and tinnitus onset
10:00 am Exploring Use & Comparison of Common Audiologic Assessments & Tests in Interventional Clinical Trials
Synopsis
- Overview of otoscopy, tympanometry, pure tone audiometry, speech discrimination, otoacoustic emissions, ABR, and electrocochleography
- Translation from animals to human using different measure or responder analysis
- Comparison of continuous vs noncontinuous variables as outcome measure or endpointsÂ
10:30 am Morning Break & Speed Networking
Synopsis
A prime chance to make the most of in-person networking and forge new connections with an expanding landscape of companies entering, or expanding their presence within, the Inner Ear therapeutics space. Designed to maximize your introduction to numerous new individuals and serve as a catalyst for ongoing discussions during the summit, connect with peers across discovery, preclinical, translational, clinical, regulatory and commercial audiological research.
Unlocking Breakthroughs in the Next Generation of Cell Therapy, Gene Therapy & Small Molecule Programs to Enhance Preclinical Success, Drive Clinical Impact & Accelerate Patient Outcomes
11:30 am Pioneering Cell Therapy to Advance from Innovation into a Clinical Reality
Synopsis
- Transition from completing preclinical work in cell therapy into becoming a clinical stage company, using the first cell therapy for audiology in patients
- Readying for later stage clinical trials and preparing for regulatory milestones for a smooth progression of a trial
- Highlighting the importance of addressing neural hearing loss within the wider hearing loss landscape and its implications for future treatment strategies
12:00 pm Accelerating Small Molecule Therapies to Drive Clinical Advancement in Inner Ear Therapeutics
Synopsis
- Exploring the achievements of initial clinical trials and outlining strategic approaches to sustain and build upon this success in later stages
- Evaluating ongoing Phase II studies and interpreting their findings to inform future development and clinical strategies
- How to plan for further clinical development, with patient enrolment in mindÂ
12:30 pm Exploring the Remote Evaluation of Hearing Function to Support Inner Ear Therapeutics Clinical Trials
Synopsis
- Discussing validation strategies, standardization of remote assessment protocols, and comparison with in-clinic evaluation
- Addressing challenges in traditional audiology evaluations, including patient accessibility, travel burden, and trial recruitment barrier
- Highlighting the benefits of continuous data collection, real-time feedback, and improved patient adherence in clinical trials
1:00 pm Speaking Position Reserved For CilCare
1:10 pm Lunch & Networking
Creating Strategic Alliances Across Biotech, Pharma & Investors to Advance Commercial & Scientific Breakthroughs in Inner Ear Therapies
2:00 pm Panel Discussion: Collaborating with Large Pharma & VCs:What are They Looking For & What to Expect?
Synopsis
- Hear from large pharma, venture capitalist and experienced biotech leaders as they dive into the scientific and commercial factors of setting up a successful partnership to develop inner ear therapies
- Uncover the key end-to-end key milestones that are evaluated when deciding on investment and partnership opportunities
- Ask your questions on what big pharma companies will be looking for next in their audiology investments
3:00 pm Afternoon Break & Scientific Poster Session
Synopsis
This is an informal session to help you connect with your peers in a relaxed atmosphere to continue forging new and beneficial relationships. With an audience of Audiology experts eager to hear the latest discoveries in Inner Ear therapeutics research, you will have the opportunity to display a poster presenting your own work and innovations. Don’t miss out on the chance to connect, learn, and present.
Talent Showcase – Organisations Take the Spotlight to Share Their Innovations in Quick Fire Rounds
4:00 pm Advancing Preclinical Cell Therapy Research for Hearing Restoration
Synopsis
- Developing a platform to characterize and manufacture auditory neurons for transplantation.
- Early preclinical animal studies show that transplanted cells are durable and demonstrate some migration.
- Preparing for regulatory discussions with the FDA while leveraging lessons from successful cell transplant programs in the spinal cord and eye.
4:20 pm Developing Small Molecule Therapies from Preclinical into Clinical Trials
Synopsis
- Advancing small molecule therapies to prevent hearing loss from antibiotics, noise exposure, and chemotherapy.
- Translating preclinical research into clinical applications for effective drug development.
- Overcoming challenges in dosing, biomarkers, regulatory pathways, and trial design.